Tens of Thousands of Associations but No Causal Mechanisms Revealed: Mismatches Between GWAS and Developmental Molecular Biology

This abstract has open access
Abstract Summary

Stephen M. Downes (University of Utah)

I argue that we should not be surprised at the disparity between the claimed success of Genome Wide Association Studies (GWAS) and lack of success at isolating underlying genetic mechanisms for the relevant human traits. I proceed by examining the mismatch in methods and assumptions between GWAS and related techniques on the one hand and developmental molecular biology on the other.

Submission ID :
NKDR342
Abstract Topics
University of Utah
183 visits